January 5, 2023 In Cannabis Research By

Research Studies Show CBD Can Help With Endometriosis?

According to the World Health Organization, endometriosis is an often painful disorder that affects approximately 10% of women worldwideEndometriosis grows endometrial-like tissue (uterine lining cells) in locations outside the uterus, including ovaries, bowels, bladder, and pelvic ligaments. The endometrium is the epithelial layer of the uterine cavity. Endometrial tissue responds to cyclic hormonal changes in the woman’s body and can bleed, much like a regular menstrual cycle. Moreover, endometriosis can cause adhesions, scarring, and painful complications when endometrial cells bleed because they aren’t shed during menstruation and attach themselves to other organs and structures around the pelvis. Endometriosis is defined as severe when women have endometrial implants that distort the pelvic anatomy or experience debilitating pain for more than six months (in which case it’s also referred to as chronic). In addition, endometriosis can cause infertility in some cases if left untreated or improperly managed. Endometriosis is often described as an autoimmune disorder because immune cells attack endometrial tissue (which they perceive as foreign), causing inflammation.

 What is CBD, and how does it work?

CBD is short for cannabidiol, one of the 100+ cannabinoids found in Cannabis. Research shows that unlike marijuana, which produces psychoactive effects when consumed. Cannabinoids like CBD have healing properties but no “high” feeling due to their non-psychoactive nature making them more beneficial for natural treatments. With that said, for centuries, Cannabis has been used to manage pain, but CBD has been receiving much attention lately due to its wide variety of potential benefits and lack of psychoactivity. CBD may help with endometriosis-associated pain by activating natural cannabinoid receptors in the body. These endocannabinoid receptors are found throughout the central and peripheral nervous system, including CB1R, considered the body’s “pain receptor.” Endocannabinoids are found in Cannabis and are produced naturally by the body. When endocannabinoids bind with CB1R receptors, they can dampen pain signals sent to the brain. CBD activates multiple pathways to reduce endometriosis-related pelvic pain. These include reducing immune cell migration to the uterus and decreasing contractions of smooth muscle cells around the blood vessels, reducing pain in patients with chronic pelvic pain.

How can CBD help with endometriosis pain management and symptoms relief?

Cannabidiol (CBD), a nonpsychoactive cannabinoid found in Cannabis with anti-inflammatory and analgesic properties, can help endometriosis patients with pain management and other associated symptoms. To illustrate, the endocannabinoid system (ECS) is a group of endogenous cannabinoid receptors located in the mammalian brain and central and peripheral nervous systems. The cannabinoids found in hemp and Cannabis mimic the endocannabinoids produced naturally by the human body. CBD works primarily through these cannabinoid receptors in the brain and central nervous system, found in nearly every type of cell in the body. Moreover, the ECS regulates many physiological processes, including appetite, pain sensation, mood, memory, and homeostasis. The endocannabinoid system has been studied for its role in various neurological and psychological conditions, such as multiple sclerosisepilepsyParkinson’s diseaseAlzheimer’s disease, and schizophrenia.

What are the side effects of CBD oil usage for endometriosis patients?

Cannabis (CBD) oil is made from the cannabis plant. It contains cancer-fighting cannabinoids that are helpful in improving endometriosis pain and inflammation. Which helps decrease the side effects of endometriosis drugs like Lupron and other similar medicines. The Endocannabinoid System and CBD Oils CB1 and CB2 receptors in the bodywork give us homeostasis. They control pain, inflammation, sleep patterns, and moods. The endocannabinoid signals that these receptors receive help them do their job of maintaining balance within our bodies. Endometriosis can disrupt this balance in the endocannabinoid system (ECS). This is because endometriosis lesions release chemicals that can irritate the endocannabinoid receptors. CBD oil helps restore balance to the ECS with anti-inflammatory, anti-neuropathic, and antioxidative properties, beneficial for pain. How CBD Oil Helps Endometriosis Patients Endometriosis has many side effects, like pain and inflammation. Women with endometriosis may experience a disrupted ECS system due to chemical signals from lesions. CBD oil may restore balance to the ECS and help improve symptoms of endometriosis and Lupron side effects like pain, inflammation, bone loss, cognitive fog, blood clots, neuropathic pain, and depression. Treatment for endometriosis ranges from natural therapies to surgical intervention. Many women have turned to Cannabis to help treat endometriosis symptoms in the past few years. Today, several surveys and studies have shown that CBD and THC are beneficial for endometriosis and the signs of the condition.


In summary, endometriosis is a disease that affects roughly 10% of women during their reproductive years. It can cause debilitating pain, irregular periods, and infertility in some cases. Symptoms include severe pelvic pain, painful periods, cramps, bloating, and nausea, resulting in chronic fatigue and loss of productivity at school or work. CBD oil may relieve endometriosis symptoms like pain, cramping, bloating, and mood swings. While there is promising research that CBD oil may help with endometriosis, more studies need to be done. We recommend visiting our site medibles.io and taking an online health assessment to personalize your CBD regimen for your unique need and profile. And if you have any questions, don’t hesitate to get in touch with one of our Bio-Health Specialists, and they can connect you with one of our doctors on our medical advisory board. To get more great content, please follow us on Social media.